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Notably, ammonium chloride, an inhibitor of CatB/L, inhibited SARS-CoV-2-S protein-driven entry into 293 T cells (TMPRSS2-negative) expressing ACE2, but less so into Caco-2 cells (TMPRSS2-positive)

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For protein identification, the raw data were processed with the software MaxQuant (version 1.6.3.3) against the Homo sapiens database (Uniprot, UP000005640) or L

Tualang honey induces apoptosis and disrupts the mitochondrial membrane potential of human breast and cervical cancer cell lines

Human cells that express ACE2 are potential targets for SARS-CoV-2 infection

However, when mitochondria are severely damaged, if fusion cannot rescue the damaged mitochondria, the damaged components or the whole mitochondria undergo fission from the healthy mitochondrial network and are eliminated via mitophagy (Youle and van der Bliek, 2012)