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Enhanced nucleotide synthesis and phosphorylation in 3D-spheroids To comprehensively understand the metabolic differences between 2D- and 3D-cultured cells, we evaluated the levels of representative metabolites using a heat map and a volcano plot (Fig

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By preventing NF-B start, KPV reduces the production of pro-swelling cytokines including TNF-, IL-1, IL-6, and IL-8