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BPC-157 has more structured preclinical toxicology behind it than the TB-500 fragment does, but neither has the long-duration and carcinogenicity data that a safety conclusion would require, and the human evidence that does exist for the TB-500 label actually belongs to a different, pharmaceutical-grade molecule

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There is, however, a synthetic analog of TH4 called TB-500, which has been investigated as a treatment for neurodegenerative conditions like multiple sclerosis, but its use is still largely experimental [4]