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The steepest descent energy minimization was performed for up to 5,000 steps, aiming for a convergence threshold with a force constant of 1,000 kJ/(mol nm)

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In addition to NIS and Pendrin, new iodine transporters, including cystic fibrosis transmembrane conductance regulator (CFTR), anoctamin 1 (ANO1), and sodium multivitamin transporter (SMVT), have recently been discovered to be expressed in these organs (2)

Betaine should also include be investigated as a supplement in large-scale clinical studies

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a position Asprey held until 2012