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The inhibition of MCTs by alpha cyano-4-hydroxycinnamic acid decreases the expression of lactate-induced pro-inflammatory cytokines in human macrophages, indicating that lactate transport through MCT is necessary for lactate effects on macrophages (109)

however, they have been useful in establishing toxicity thresholds for a number of diverse taxa that have been exposed to numerous types of oils (at differing weathering states), hydrocarbon mixtures, or single hydrocarbon components

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Their canonical activity is the degradation of ECM proteins, even if they exhibit pleiotropic functions, modulating a diverse array of biological processes, such as cell migration, leukocyte activation and inflammatory responses [89, 92]

Letter to the Editor Combination therapy of glutathione and resveratrol a promising approach in the management of melasma Abdullah Demirba Gzde Uluta International Journal of Dermatology 63(8):p 1108-1110, August 2024