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Additionally, AI-driven disease progression models could optimize delivery timing, while metabolic profiling data may guide the development of systems targeting renal urate transporters (e.g., mURAT1), enhancing intervention precision for chronic metabolic disorders

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Furthermore, quantification of hepatocellular vacuolation (a characteristic of cellular degeneration observed through tissue pathology staining) at the 2-h time point revealed a 1.5-fold greater area of liver degeneration in hepsin / mice compared with wild-type mice, which increased to ~ 2.5-fold greater by the 6-h time point (Fig