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The choice of the type and concentration of local anesthetic should be based on whether the block is planned for surgical anesthesia or pain management ( Table 2 )

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Late signs of cyanide toxicity include hypotension, complex arrythmias, cardiovascular collapse, pulmonary oedema, and death

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The mean absolute bioavailability following intramuscular injection was approximately 14-19% in rats and 45-51% in beagle dogs, suggesting species-specific absorption characteristics relevant for dose translation to human applications