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Because the COX-2 gene is a direct downstream target of NF-B, curcumins blockade of the NF-B pathway directly results in the suppression of new COX-2 enzyme production

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There was a lower green fluorescence intensity in the ZFPG group than the ZFP group with the same treated concentration, demonstrating the cascade catalysis effect of ZFPG NPs could enhance the GSH consumption-ability

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