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This is probably due to the differing levels of susceptibility of different brain regions to OS

PMID: 21962263

Plant Physiol 171:707719 Cobbett CS (2000) Phytochelatin biosynthesis and function in heavy-metal detoxification

(INS 460(i)), (INS 470(iii))

Although the specific mechanisms by which gender influences systemic metabolic variations in PD patients with mutations in GBA1 , LRRK2 , TMEM175 , PARK2 , PINK1 , and PARK7 are not yet fully understood, taken together our NMR results indicates that sex plays a prominent role in shaping unique serum metabolomic profiles in familial PD compared to controls

On the other hand, smaller numbers denote a larger diameter or width