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Blood samples from the mice were centrifuged at 300 g for 8 min at 37C, and the supernatants were measured using an alanine aminotransferase (ALT) kit (HuiLi Biotech Co., Ltd., Changchun, China) and an aspartate aminotransferase (AST) kit (Jiancheng Bioengineering Institute, Nanjing, China), according to the manufacturer's protocols

Reversal of nephrotoxic effect of cyclosporine by medicinal plants Cyclosporine A is an immunosuppressive administered following solid organ transplantation to prevent rejection and treat autoimmune diseases

Additionally, inflammatory cytokines and chemokines released by immune cells can activate signaling pathways that support tumor growth and survival [111]

An important challenge for future studies will be to define which nodes within this multilayered GSH-centered defense network represent true therapeutic vulnerabilities across different tissue and tumor contexts

[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Grlach A., Bertram K., Hudecova S., Krizanova O