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3 Higher-risk MDS has a poorer prognosis, with up to 40% of patients experiencing deterioration or progression to AML within two years of diagnosis

doi: 10.3389/fbioe.2025.1695821 Received 30 August 2025 Revised 03 November 2025 Accepted 17 November 2025 Published 12 January 2026 Corrected 06 February 2026 Volume 13 - 2025 Edited by Tommaso Del Rosso, Pontifical Catholic University of Rio de Janeiro, Brazil Reviewed by Anna Laurenzana, University of Florence, Italy Anastasia Chill, University of Florence, Italy Yuliia Shlapa, V

Biological/Genetic Factors in Anorexia (01:09:44) Chemical Imbalances, Serotonergic Treatments (01:12:56) Altered Habits & Rewards in Anorexia: Hyperacuity for Fat Content (01:18:28) Brain Areas for Reward Based Decision Making vs

Within lysosomes, the intracellular milieu characterized by proteolytic enzymes, acidic pH, or reductive redox conditions facilitates payload release, contingent on the design of the chemical linker

The significance of Pgp-MDR has been most thoroughly documented in hematological malignancies

Statistical analysis Statistical analysis and graphing were conducted using GraphPad Prism version 8.0.2