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Further studies in the 2000s, (7) suggested that the GHK-Cu peptide hosts the potential to not only stimulate the collagen synthesis but also stimulate the production of tissue inhibitors, TIMP-1 and TIMP-2

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it delayed markedly the in vivo subcutaneous growth of the D283-Med xenograft and, more importantly, it increased by over 40% the OS when administered to mice with intracranial MB tumor xenograft

All of the studies used both in vivo and some form of in vitro methods of data collection in order to observe different treatment effects, allowing for biomechanical, functional (use of AFI index and load to failure), macroscopic and microscopic histological analysis

Ma GY, et al