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Olszanecki, R., et al

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Unlike heat exposure, which causes gradual degradation, freezing can destroy a significant percentage of active peptide in a single event

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However, this increase in BUN is also affected by other factors: the concomitant loss of HS at least in part explains the increase in BUN and fully explains the CLP-induced decrease in glomerular filtration rate (GFR) (98)

Timing is everything when it comes to supplements, said Gadre.