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Menthol cigarettes have been banned in several countries, including Australia, Canada, Ethiopia, all member states of the European Union, Moldova, Turkey, the United Kingdom, and some areas of the United States, including California, the District of Columbia, and Massachusetts

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Compared with traditional meta-analysis using linear mixed effect models, MR-BRT relaxes the assumption of a log(linear) relationship between exposure and risk, incorporates between-study heterogeneity into the uncertainty of risk estimates, handles estimates reported across different exposure categories, automatically identifies and trims outliers, and systematically tests and adjusts for bias due to study designs and characteristics