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Potential Long-Term Risks Although AOD-9604 does not increase IGF-1 levels, there are concerns about its long-term metabolic effects, including: Unknown impact on fat metabolism regulation Since AOD-9604 alters fat-burning pathways, researchers are still investigating whether prolonged use could affect natural fat metabolism

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Anti-inflammatory genes upregulate while pro-inflammatory pathways decrease

Since youre absorbing smaller amounts over time, it may take longer to notice improvements

A diagnosis of hypothyroidism results in a slowed metabolism, which in turns needs to low stomach acid and the inability to naturally break down and extract key nutrients through food, no matter how clean and fresh one eats

Earlier studies introduced reporting bias, lacked a control group, did not adjust for confounding factors, failed to assess menstrual characteristics other than cycle length, or lacked sufficient follow-up length