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They further modified DMB and developed inhibitors targeting CutC and CutD, the major microbial TMA-generating enzyme pair, and when administered as a single oral dose, significantly decreased plasma TMAO concentrations for up to 3 days and rescued the diet-induced enhancements in platelet reactivity and thrombosis in animal models, without increasing bleeding risk or toxicity (Roberts et al., 2018)

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pmid:12023119 Rosario ER, Chang L, Head EH, Stanczyk FZ, Pike CJ (2011) Brain levels of sex steroid hormones in men and women during normal aging and in Alzheimers disease

Multiple human and animal studies have demonstrated that specific gut bacterial taxa influence TMA production

If your doctor suggests using ALCAR, work with them to find the optimal dosage according to your health condition and other factors