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In the nucleus, following heterodimer complex formation with transcription factors, like small Maf proteins (G/F/K) and c-Jun, Nrf2 complexes bind to the antioxidant response element (ARE), a regulatory enhancer region within gene promoters that upregulate antioxidant and anti-inflammatory defense processes (Cuadrado et al., 2019

Similar content being viewed by others Introduction Liver cancer, primarily HCC, is among the most challenging tumors to treat, ranking sixth globally in incidence and third in cancer-related deaths

In parallel to the finding of Wang et al., Gialluisi et al

312,316,317 Notably, the nucleic acid molecules in these conjugates are directly exposed to serum

Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function