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De vorming van vrije radicalen kan het gevolg zijn van overmatige blootstelling aan UV-straling, vervuiling, tabak

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Li M, Cui H, Deng H, Deng Y, Yin S, Li T

Conclusions and perspectives By integrating mechanistic insights and disease-specific evidence, this review delineated how ATFs orchestrate macrophage development, survival, migration, phagocytosis, activation, cytokine secretion and polarization and how these regulatory axes converge to shape macrophage-driven pathology in infectious, inflammatory, metabolic, oncologic and neurodegenerative settings