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These active metabolic functions cause increased nutrient consumption, resulting in decreased immune function and increased risk of infection

Unlike the monoamine system with the main role of providing extrinsic inputs to the cerebral cortex, Glutamate provides both excitatory and inhibitory control of information flow in the brain (132, 137, 138)

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It is a cofactor to enzymes that help move glucose across cell membranes when breaking down carbohydrates for energy, specifically in the liver

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Heparan sulfate-modified CD44 promotes hepatocyte growth factor/scatter factor-induced signal transduction through the receptor tyrosine kinase c-Met