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Data from the journals were collected at test sessions 2 and 3

Onset times by method: Vaping/E-cigarettes : 5-10 seconds, reaching your brain within 30 seconds Cigarettes : 7-10 seconds, with peak levels at approximately 7 minutes Fast-acting pouches (LOOP) : 10-30 seconds using rapid-release technology Nicotine gum : 15-30 seconds with proper chew-and-park technique Standard/ZYN pouches : 1-3 minutes depending on moisture content The nicotine high length you experience correlates directly with these onset times

Biol Fertil Soils 41, 135143, 10.1007/s00374-004-0829-0 (2005)

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