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In all three tested HCoVs (OC43, 229E, and SARS-CoV-2), G12(S) can repress infectious virus production despite its inefficient suppression of vRNA levels in the culture medium

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Our research indicates that myofibroblast markers, such as alpha smooth muscle actin (-SMA), are more prevalent in fibroblasts from aged mouse lungs compared to younger controls (Figure 3), highlighting the age-dependent increase in fibrosis susceptibility

Woulds were induced on each rabbit and the rabbits were presented with the respective compounds for 21 consecutive days

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