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FOXO4-DRI targets senescent cells, which disrupt natural testosterone production, potentially restoring hormonal balance

The peptide also increases integrin expression in basal keratinocytes at concentrations of 0.1-10 micromolar, enhancing p63 positivity, a transcription factor that maintains stem cell characteristics

NPJ Biofilms Microbiomes 8 (1), 89

The apparent paradox in this dual-face role of ROS, regulation of cellular functions versus toxic by-products of metabolism, can be reconciled considering differences in the amount of ROS production