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For the analysis, researchers used medical information on 249,190 people, including 203,932 who reported never using e-cigarettes or combustible cigarettes (203,932), 3,164 who reported exclusively using e-cigarettes, 33,778 who reported exclusively using combustible cigarettes, and 8,316 who reported using both e-cigarettes and combustible cigarettes

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Vape aerosols still contain potentially harmful substances, including: Nicotine Ultrafine particles Heavy metals Volatile organic compounds Chemical flavoring agents Certain flavoring chemicals have been linked to airway irritation and inflammation