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Larsen DL, Gandhi H, Pollack M, et al

The copper ion may dissociate from the GHK tripeptide, and free copper ions are pro-oxidant

While extensively studied in preclinical and small clinical settings, GHK-Cu lacks FDA approval as a pharmaceutical agent and is primarily available in cosmetic formulations for topical use

Evidence of liver functional maturation is supported by glucose- 6-phosphatase (G6P) transcript enrichment at day 20 compared to day 4 (Van Every & Schmidt, 2021)