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Understanding your bodys response is important

[23] What side effects should I watch for

It is used for the treatment of a wide variety of medical conditions such as osteoarthritis and rheumatic disorders

Eur J Nutr 2016;55:281-93

NNMT inhibition increases cellular concentrations of both substrates that the enzyme would otherwise consume: SAM (the universal methyl donor) and nicotinamide (the NAD + salvage precursor)