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210 Various chemotherapy drugs can directly or indirectly affect Tregs in tumors, thereby influencing their therapeutic efficacy (Fig

In contrast, PHGDH knockout attenuates tumor growth, reduces TAM infiltration, promotes the phenotypic conversion of M2-like TAMs to an M1-like state, downregulates PD-L1 expression, and consequently enhances antitumor T-cell immunity ( Serine generates multiple pivotal metabolites through the one-carbon metabolic pathway (SGP), regulating the development, proliferation and differentiation of CD8 + T cells, effector T cells and regulatory T cells (Tregs)

These biochemical stressors are generally removed from the body by glutathione for remediation

First, vitamin C is not patentable