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The International Agency for Research on Cancer (IARC), operating within the World Health Organization (WHO), classified GLY as probably carcinogenic to humans (2A) in March, 2015 (IARC 2015

Breaking of these disulfides, possibly by reduced PDIp, leads to activation of the enzymatic activity

Inflammatory cytokines can inhibit the ability of blast-forming unit-erythroid or BFU-E to differentiate or alter the bone marrow environment, affecting erythropoiesis

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Yang L, Zheng XL, Sun H, Zhong YJ, Wang Q, He HN, et al