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Pharmaceutics 13, 136 (2021)

Another critical challenge is the lack of well-defined immunological correlates or biomarkers of protection

The research results showed that hazelnut leaf polyphenol extract significantly increased the intestinal microbial diversity and decreased F/B values in HFD fed mice, elevated the intestinal content of SCFAs, reduced the expression of lipid synthesis-related proteins SREBP1c, PPAR and CCAAT/enhancer-binding protein alpha (C/EBP), and promoted the phosphorylation level of adenosine 5-monophosphate (AMP)-activated protein kinase (AMPK)

Over time, poorly controlled blood sugar increases the risk of cardiovascular disease, nephropathy, retinopathy, and neuropathy

This article summarizes in understandable language the elements of metabolism that are necessary to appreciate both the mechanisms and conclusions arrived at through a series of studies published in very well respected journals by a group of scientists Ill label the Stephens Group

[DOI] [PMC free article] [PubMed] [Google Scholar] Seidl R, Cairns N, Singewald N, Kaehler ST, Lubec G