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418,419 The efficiency of CDT is closely related to the H 2 O 2 content in the disease microenvironment, so researches have focused on introducing functional components on MSNs matrix to enhance the content of H 2 O 2 reactants, thus increasing the yield of OH

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The principles of this approach are that treatment is based on the best available research evidence, the expertise of the clinician as applied to the diagnosis and overall health status of each patient coupled with assessment of the riskbenefit balance of potential therapies, and the preferences and values of the patient

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