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Paul, Minnesota 55121 -2097, USA Kurita T (2019) Principal component analysis (PCA)

297 Mitochondrial dynamics also modulate CSC behavior through coupling with mitophagy

6.2 Genetic forms and oxidative cross-talk (PINK1/Parkin, DJ-1, LRRK2, GBA1) 6.2.1 PINK1/Parkin mitophagy failure ROS spillover Loss-of-function along the PINK1Parkin axis impairs clearance of damaged mitochondria, increasing ROS and sensitizing dopaminergic neurons to oxidative injury