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Activation in the area postrema (AP) The area postrema is a circumventricular organ , a region of the brain that has no blood-brain barrier , so peptide hormones from the blood have direct access to it

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It functions as a tissue-repair signal, sending instructions to local cells about wound healing, inflammation control, collagen synthesis, and, relevant here, hair follicle maintenance.4 Instead of opening a single channel or extending a single phase of the hair cycle, GHK-Cu acts as a regulatory signal across multiple pathways

That provides some evidence for AOD-9604's potential as a weight loss drug