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The Glutamate Hypothesis Initially proposed in 1980 after glutamate levels were seen to be lower in the cerebrospinal fluid of schizophrenia patients (128), the glutamate hypothesis postulates that the negative symptoms seen in schizophrenia are in part linked to dysfunctional glutamatergic signalling, mediated by NMDA receptors on GABAergic interneurons (129), with the induced psychosis caused by NMDA receptor antagonists resembling schizophrenia symptoms more closely than those that act on the dopaminergic system (130)

In fetuses infected with HCMV, there is a significant increase in the percentage of activated and terminally differentiated CD8 + T cells in umbilical cord blood, including both HCMV-specific and nonspecific T cells [209]

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Intravenous Injections Intravenous injections are the most common method of administering glutathione for skin lightening

single bolus Result:Produced a significant 36% increase in baseline hindquarter vascular resistance at 120-180 min post-treatment

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