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To assess the potential role of PVN Glu neurons in modulating morphine-induced constipation, we directly infused morphine into the bilateral PVN through implanted cannulas (Fig

doi: 10.1016/j.smim.2007.10.011 33 DuJHuangCZhouBZieglerSF

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Therefore, varying drugs, including antidiabetics, antioxidants, lipid-lowering drugs, probiotics, and anti-platelets, which might have potential beneficial effects, have been continuously investigated in patients with CLD [8-15]