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One of the primary functions of glutathione is to neutralize a broad spectrum of free radicals and to relieve oxidative stress

The combined use of MR and the TXNRD inhibitor auranofin demonstrates notable antitumor effects in PDX TNBC mouse models (59)

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One common type of phosphonate backbone modification is the addition of a methylphosphonate (MeP) linkage, which replaces one of the non-bridging oxygen atoms of the phosphodiester bond with a methyl group, creating a non-ionic and chemically stable linkage [66]

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