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Different small molecules may target different components of the tyrosine kinase signaling cascade

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The 3D structure of the compound T1 , T2 , T3 and T5 were generated and optimized by energy minimization using Discovery Studio v.4.0 (Accelrys Software Inc., USA)

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These screens identified PCBP2 as a chaperone involved in facilitating iron uptake and efflux in HEp-2 cells (Yanatori et al., 2014