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Besides this, there is an increase in the generation of NADPH and GSH, an antioxidant, and redox cofactors such as NADH and FADH

However, compound 34 with a 5-chloro-2-fluoro substituted phenyl ring displayed the highest EC 50 in the RNA reduction-based assay and had considerably higher EC 50 in the CPE-based assay compared to other halide-substituted ebselen diselenide derivatives ( 25 , 27 , 30 )

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Powerful Antioxidant Protection Glutathione neutralizes harmful free radicals, helping to protect cells from oxidative damage linked to conditions like heart disease, cancer, and diabetes