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Signs, symptoms, and health problems associated with vitamin B12 deficiency Characteristic signs, symptoms, and health problems associated with B12 deficiency include anemia, fatigue, weakness, constipation, loss of appetite, and weight loss [1,3,12]

48-52 On the other hand, alertness is associated with better mood and cognitive, mental, and physical performance

doi: 10.1007/s13205-017-0786-6 49

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This distinction has important implications: the platform cannot prescribe medications, cannot make medical determinations, and cannot guarantee prescription approval

Modifications to be read simultaneously can be on the same histone tail, but they can also be further apart on the same nucleosome, on neighboring nucleosomes, or on nucleosomes that are not close on a contiguous stretch of DNA but are spatially located in common chromatin territory