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Larger Trials and Longer-Term Findings Furthermore, a larger RCT of 140 participants observed significant improvements on global symptomatology and general and negative symptoms of schizophrenia in the NAC supplementation (2 g/d

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In aged mice, in vitro inhibition of mTORC1 with metformin or everolimus increased IL-2 production and T cell proliferation and reduced oxidative stress in CD4 T cells 28