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Recently, it has been shown that long-term E2 withdrawal of ER-positive breast cancers triggers to the stable epigenetic activation of the MVA pathway and cholesterol synthesis ( de novo biosynthesis of androgens from cholesterol activates androgen receptor (AR) activity in castration resistant disease (99), thus suggesting a role for the MVA pathway in prostate cancer progression, also considering the observations that SREBP expression is enhanced in advanced stages of prostate cancer

Reproductive toxicity of primary and secondary microplastics to three cladocerans during chronic exposure

Nontuberculous mycobacterial infections after cosmetic procedures: a systematic review and management algorithm

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Elevated cortical extracellular fluid glutamate in transgenic mice expressing human mutant (G93A) Cu/Zn superoxide dismutase

Metabolomic analysis of a human oral glucose tolerance test reveals fatty acids as reliable indicators of regulated metabolism