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HLC cultures were incubated with conventional probe substrates for CYP3A4 (6 M midazolam), CYP2C9 (10 M diclofenac), and CYP2D6 (10 M dextromethorphan) for 2 hours

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Similarly, a 2017 double-blind, placebo-controlled trial found that oral administration of ALA (1,200 mg/day) for eight weeks induced mild weight loss accompanied by a reduction in waist circumference

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