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Compared with other control cells, these senescent cells expressed abundant secretory factors and metabolites that promoted the pathogenesis of atherosclerosis, concurrent with significant alterations in epigenetic imprints

The main issue with seed oils is that they present an oxidative liability

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As such, the growing body of evidence underscores the need for increased regulation of these chemicals, particularly those that are known to exhibit endocrine-disrupting properties (51, 65, 6871)

Protein kinase B/AKT mediates insulin-like growth factor 1-induced phosphorylation and nuclear export of histone deacetylase 5 via NADPH oxidase 4 activation in vascular smooth muscle cells