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Its inhibition induces autophagic flux in cancer, inflammation, and infection models but may also promote EMT, depending on the context

has received funding support from Hoffman-La Roche, Ferring Pharmaceuticals and NovImmune and during the past 5 years has acted as an advisory consultant for Roche, Chugai Pharmaceuticals, NovImmune, Genentech, Sanofi Regeneron, Johnson & Johnson, Janssen Pharmaceuticals, Eleven Biotherapeutics and UCB

Neuroinflammation and Oxidative Stress Neuroinflammatory and oxidative stress are among the brain-health themes that have been recognized in the reviewed articles

Results Patient demographics and disease characteristics We recruited 20 male subjects meeting the 2015 ACR/EULAR gout classification criteria, with mean age 60.4 years (11.1) and mean body mass index (BMI) of 31.5 (4.4)