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By explicitly mapping these relationships, the review underscores how discrete metabolic pathways in CSCs and immune subsets converge to shape ICI resistance, and how metabolic interventions offer rational strategies to restore therapeutic efficacy

Heightened anxiety-like phenotypes are consistent with prior work linking prenatal THC and gestational stress to altered HPA axis function and emotional circuit maturation [50, 51, 52, 53], although HPA activity was not directly assessed here

Metallothionein is downstream of Nrf2 and partially mediates sulforaphane prevention of diabetic cardiomyopathy

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