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When discussing how long peptides stay in the system, two terms are particularly important: half-life and detection time: WORTH NOTING: Natural peptides typically have short half-lives, often just minutes to an hour, due to rapid enzymatic degradation, while synthetic peptides can be designed to last longer, with half-lives ranging from hours to several days

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2,7,8,9 Moreover, comorbidities linked with AD may exacerbate the health condition of patients, contributing to clinical phenotype diversity and accelerating cognitive dysfunction