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detailed that targeting mitochondrial dysfunction to prevent liver disease progressions includes altering metabolic signaling cascades to increase energetic efficiency, mitigating ROS/RNS, and restoring mitophagy and other systems to maintain homeostasis within mitochondria [91]

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In theory, combining agents that both reduce adiposity and improve insulin sensitivity could produce additive or synergistic metabolic effects but this is entirely speculative and unproven in humans

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Int J Pharm Yehuda S, Carasso RL (1988) DSIP: brain mechanisms and function

Transmission Electron Microscope The hippocampal tissue of rat brain was excised and stored at 4 by adding electron microscopic fixative