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The mixed-gender SOD1 G93A GPX4 mice (n = 35) had mean, median and maximum lifespans of 169, 170, and 186 days respectively, while the mixed-gender SOD1 G93A mice (n = 30) had mean, median and maximum lifespans of 160, 161.5 and 175 days respectively

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10.1007/s12035-015-9652-x 366 ZhangL

Moreover, various CRP polymorphisms and mutants will result either in adverse or favorable responses in acidic inflammatory microenvironments