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That could affect blood vessels' ability to respond to increased demands from the heart

Results: Among all surveyed teachers, 13.9% reported smoking cigarettes, and 76.6% did not meet the physical activity recommendations

So, with fewer people having a history of smoking, there is a higher chance of diagnosing lung cancer that is not attributable to smoking. Nature paper note: With smoking rates declining, [lung cancer in never-smokers] might eventually predominate lung cancer diagnoses. Genetic Mutations People who have never smoked but get lung cancer often have genetic mutations in their cancer cells that contribute to cancer development

Nicotine is a stimulant that can increase alertness and make it harder to fall asleep

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