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Weikel 2012

Proc Natl Acad Sci U S A 91(21):1005910063 May MJ, Leaver CJ (1994b) Arabidopsis thaliana -glutamylcysteine synthetase is structurally unrelated to mammalian, yeast, and Escherichia coli homologs

Nitric oxide, observed during the inflammatory phase of wound healing, has been shown to compromise collagen accumulation, which is a crucial process in skin health

Knee replacement surgery can effectively alleviate pain, improve joint function, and restore mobility, enabling patients to return to their daily activities with reduced pain and improved quality of life

Estrogen has an antioxidant function, and estrogen deficiency can inhibit the Nrf2/GPX4 pathway to induce ferroptosis (73)

Cell growth, controlled by sodium-hydrogen ion exchangers (NHEs), induces MIC-dependent activation of the PI3K/Akt pathway, which in turn supports the cytoplasmic localization of the cell cycle inhibitor p27 Kip1 , resulting in tumor cell proliferation [142]