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*Correspondence: Pavel Dietz [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Together, these findings indicate that smoking even a small number of cigarettes per day has substantial negative health effects and provide further evidence that smoking cessation benefits all smokers, regardless of how few cigarettes they smoke. About the National Cancer Institute (NCI): NCI leads the National Cancer Program and the NIHs efforts to dramatically reduce the prevalence of cancer and improve the lives of cancer patients and their families, through research into prevention and cancer biology, the development of new interventions, and the training and mentoring of new researchers

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As health studies continued to demonstrate the negative health effects of smoking, tobacco companies began offering safer and healthier alternatives of smokeless tobacco, often using ballplayers as pitchmen