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Additionally, KD has been shown to suppress apoptosis in hippocampal neurons by downregulating the AMPK pathway and reducing HSP70 expression [51]

In PD treatment, delivering dopamine via nanocarriers has proven to be an efficient and viable strategy

Furthermore, -adrenergic stimulation could induce HSL enzyme activity, whereas insulin exerts inhibitory effects on both HSL expression and phosphorylation [82, 83]

However, the CSC pool itself is not homogeneous

Both 25-hydroxylases (CYP2R1 and CYP27A1) were expressed in the liver, while CYP27A1 expression was seen only in cultured hepatocytes (FL83B mouse hepatocyte cell line)

However, the regulatory mechanism of ferroptosis has not been fully elucidated and the investigation still faces challenges